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The DFG Research Unit FOR2722 "Novel molecular determinants for musculoskeletal extracellular matrix homeostasis - a systemic approach" in Cologne are organising a series of seminars with national and international speakers presenting work in musculoskeletal health and ECM homeostasis. The Seminars are live and free to attend, and feature a get-together for PhD students after the seminar, to facilitate face-to-face interactions that are essential for building relationships and forging collaborations with internal and external researchers.



Upcoming Events

13 March

"Deciphering the role of secretory pathways in the reciprocal connection between the cellular nutrient sensing machinery and the extracellular matrix"


10 April

"The extracellular matrix in non-classical osteogenesis imperfecta"


08 May

"Unravelling of novel pathomechanisms for bone and cartilage diseases"


12 June

"Musculoskeletal ECM-induced reprogramming of the metabolic system"


10 July

"Mitochondrial dysfunction in cartilage and its consequences for ECM and joint homeostasis"


11 September

"Collagen XII as a risk factor for musculoskeletal diseases"


09 October

"Collagen VI assembly and function in musculoskeletal disorders"

The European Calcified Tissue Society (ECTS) are organising a webinar entitled "Mechanical loading and bone development" on the 22nd of January at 4pm CET, with live Q&A session with the audience.


Chair: Dr Maria Carolina Medina Gomez, Erasmus MC Rotterdam, Rotterdam, Netherlands

Speaker: Dr Alex Ireland, Manchester Metropolitan University, Manchester, UK

 

Abstract

Due to the short levers muscles work with, muscular forces produced during physical activity provide by far the largest routine stresses which the bones experience. Bone readily adapts to this loading, such that physical activity is arguably the key determinant of postnatal bone shape and structure. Despite this, the efficacy of exercise interventions to improve bone health in adults has been limited. During this session we will discuss the associations described above, and factors that may explain the inability to translate our knowledge in this area into clinical therapies. We will discuss how clinicians can safely advise on physical activity, and conclude by examining the important role that the earliest exposures to muscular action prenatally and in infancy have in determining bone mass.

 

Registration

This webinar is free and open to everyone with an interest in the field. Webinar link: https://ectsoc.org/event/bmb-23jan25/


 
 
 

We have achieved a lot in our second year as a consortium. Our DCs have been on several secondments, presented their data at national and international meetings, and contributed to several publications. We have had a great annual meeting in Vienna, a successful summer school in Lyon, and we are looking forward to our next annual meeting in Krakow.


Read all about these (and more) in our second annual newsletter here:


or download the PDF file:



 
 
 
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