The Role of Calcium in Osteoblastogenesis - a webinar by Prof Antonella Forlino, 21st September 4pm

The webinar will address the more recent discoveries of the role of Calcium flux in modulating osteoblastogenesis and bone formation. In vitro and in vivo models, knock out for the endoplasmic reticulum trimeric potassium channel TRIC-B, associated to the recessive OI form type XIV, will be presented and discussed.

Key takeaways:

• Learn about the generation and characterization of knock out cell lines using CRISPR/Cas

• Learn about the effect of impaiment of calcium flux through the endoplasmic reticulum in bone forming cells

• Learn about generation and characterization of knock out zebrafish to investigate OI type XIV

• Learn about generation and characterization of conditional knock out mice to investigate OI type XIV

Format: Webinar of 45 minute with presentation by Antonella Forlino followed by 15 min discussion.

Joining: Please sign up through the Care4Bones page for the event by indicating “Are you attending: Yes”. If you are not on Care4Bones yet, please join or request the joining instructions from info@care4bones.org.

ECTS webinar on bone marrow adipocytes, 17th August 4pm CET

The European Calcified Tissue Society (ECTS) are organising a webinar entitled "Bone, Muscle & Beyond: Bone marrow adipocytes as novel regulators of metabolic homeostasis, immune function, and skeletal health" on the 17th of August at 4pm CET, with live Q&A session with the audience.

The webinar covers the topics below:

• Bone marrow adipose tissue (BMAT) is a major adipose subtype that is developmentally and functionally distinct from other classes of adipose tissue.

• BMAT can influence metabolic homeostasis, haematopoiesis and skeletal remodelling, both in normal physiology and in disease settings.

• BMAT increases or decreases in diverse clinical contexts, including ageing, osteoporosis, type 2 diabetes and chronic kidney disease. Current research is now aiming to establish if BMAT directly influences pathogenesis of these diverse disease

To register for the webinar, please click: https://ecampus.ectsoc.org/db6107e21812f585

Interesting EV and senescence meetings this year

There are several interesting meetings on Extracellular Vesicles and Senescence coming up this year:

Austrian Society for Extracellular Vesicles in Graz: https://www.asev.at/congresses.php

International Society for Extracellular Vesicles in Seattle: https://www.isev.org/index.php?option=com_jevents&task=icalrepeat.detail&evid=169&Itemid=115&year=2023&month=05&day=17&title=isev2023-annual-meeting-&uid=f2dd6e1d3bef4c2ade16b310dd1be9d3

Senescence in vivo in Wien: https://show.lbg.ac.at/senescenceinvivo/