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The European Calcified Tissue Society (ECTS) are organising a webinar entitled "Population (gen)omics in osteoarthritis: identification of causal biological mechanisms and clinical impact" on the 18th of July at 4pm CET, with live Q&A session with the audience.


Chair: Dr Maria Carolina Medina Gomez, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands

Speaker: Dr Cindy G. Boer, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands

 

Learning Objectives

  • What GWAS studies are used for and what we have identified in terms of the genetic architecture of Osteoarthritis risk

  • How functional omics can translate GWAS findings into biology, pathways

  • How genetics can contribute to clinical applications, particularly in Osteoarthritis

 

Registration

This webinar is free and open to everyone with an interest in the field. Webinar link: https://ectsoc.org/event/bmb-jul2024/


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Craniosynostosis is a congenital condition involving the premature fusion of one or more cranial sutures during a newborn's development, caused by mutations in multiple genes. A commonly affected gene is FGFR2, which has various mutations linked to syndromic forms of craniosynostosis such as Crouzon, Apert, and Pfeiffer Syndromes. This webinar will cover the creation of human adult and pluripotent stem cells derived from craniosynostosis patients, and the application of genome editing techniques to develop and study disease models of monogenic bone disorders.

 

Key takeaways

  • Explore the processes involved in creating human adult and pluripotent stem cells from patients with craniosynostosis.

  • Discover the techniques and applications of genome editing used to generate and study disease models of monogenic bone disorders.

  • Understand how disease models are developed and utilized to study the pathology and potential treatments for craniosynostosis and other monogenic bone disorders.


Format: Webinar of 30 minutes of research topics of Genome editing and in vitro disease modelling by Dr. Jeroen van de Peppel followed by a discussion.


Joining: Please sign up through the Care4Bones page for the event by indicating “Are you attending: Yes”. If you are not on Care4Bones yet, please join or request the joining instructions from info@care4bones.org.


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The European Calcified Tissue Society (ECTS) are organising a webinar entitled "Quo vadis animal experimentation in skeletal research?" on the 20th of June at 4pm CET, with live Q&A session with the audience.


Chair: Dr Maria-Bernadette Madel, Baylor College of Medicine, Texas, USA

Speaker: Prof Dr Jan Tuckermann, Ulm University, Ulm, Germany

 

Learning Objectives

  • Strength and limitations of animal models, non-animal models, and in sillico approaches

  • Improving reproducibility as a responsibility for science and animal welfare

  • The use of experimental animals in the current research landscape and the regulations

  • The holistic approach: choosing the right models to have the best science with the least harm to animals

 

Registration

This webinar is free and open to everyone with an interest in the field. Webinar link: https://ectsoc.org/event/bmb-jun2024/


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